1)Dichlorvos 95% 98%TC10%25%75%WP 50%SC 70%WDG
2)Quality Certificate by SGS
Common name dichlorvos (BSI, E-ISO, (m) F-ISO, BAN, ESA); DDVP (JMAF); dichlorfos (USSR); DDVF* (former exception, USSR)
IUPAC name 2,2-dichlorovinyl dimethyl phosphate
Chemical Abstracts name 2,2-dichloroethenyl dimethyl phosphate
CAS RN [62-73-7] EEC no. 200-547-7 Development codes Bayer 19 149; C 177 (Ciba) Official codes OMS 14; ENT 20 738
Mol. wt. 221.0 M.f. C4H7Cl2O4P Form Colourless liquid; (tech., colourless-to-amber liquid, with an aromatic odour). B.p. 234.1 /1 ?105 Pa (OECD 103); 74 /1.3 ?102 Pa V.p. 2.1 ?103 mPa (25 ) (OECD 104) KOW logP = 1.9 (OECD 117); 1.42 (separate study) Henry 2.58 ?10-2 Pa m3 mol-1 S.g./density 1.425 (20 ) (OECD 109) Solubility In water c. 18 g/l (25 ). Completely miscible with aromatic hydrocarbons, chlorinated hydrocarbons and alcohols; moderately soluble in diesel oil, kerosene, isoparaffinic hydrocarbons, and mineral oils. Stability Stable to heat. Slowly hydrolysed in water and in acidic media, and rapidly hydrolysed by alkalis, to dimethyl hydrogen phosphate and dichloroacetaldehyde; DT50 (est.) 31.9 d (pH 4), 2.9 d (pH 7), 2.0 d (pH 9) (22 ). F.p. >100 (DIN 51758); 172 (Pensky-Martens closed cup, 1 ?105 Pa)
History Insecticide described by Ciba AG (now Syngenta AG) (GB 775085), but an incorrect structure given to the compound; later reported by A. M. Martson et al. (J. Agric. Food Chem., 1955, 3, 319) as an insecticidal impurity in trichlorfon. Introduced by Ciba AG, Shell Chemical Co. (now BASF AG), and Bayer AG. First marketed by Ciba in 1959. Patents GB 775085 to Ciba-Geigy; US 2956073 to Shell Manufacturers Aimco; Amvac; Denka; DE-NOCIL; Hindustan; Jin Hung; Lucava; Makhteshim-Agan; Nagarjuna Agrichem; New Chemi; Nippon Soda; Q.E.A.C.A.; Rallis; Reposo; Sanonda; Shenzhen Jiangshan; Sudarshan; Syngenta; United Phosphorus
Biochemistry Cholinesterase inhibitor. Mode of action Insecticide and acaricide with respiratory, contact, and stomach action. Gives rapid knockdown. Uses Control of household and public health insect pests, e.g. flies, mosquitoes, cockroaches, bedbugs, ants, etc.; stored-product pests in warehouses, storerooms, etc.; flies and midges in animal houses; sciarid and phorid flies in mushrooms; sucking and chewing insects, and spider mites in a wide range of crops, including fruit, vines, vegetables, ornamentals, tea, rice, cotton, hops, glasshouse crops, etc. Also used as a veterinary anthelmintic. Phytotoxicity Non-phytotoxic when used as directed, except to some varieties of chrysanthemum. Formulation types AE; EC; GR; HN; KN; OL; SL; Impregnated strip. Compatibility Incompatible with alkaline materials, chinomethionat, and dichlofluanid. Selected tradenames: 'Dedevap' (Bayer); 'Nuvan' (Syngenta); 'Vapona' (agronomic uses only) (BASF); 'Amidos' (Aimco); 'Charge' (Sanonda); 'Dash' (Nagarjuna Agrichem); 'Denkavepon' (Denka); 'Divipan' (Makhteshim-Agan); 'Doom' (United Phosphorus); 'Hilvos' (Hindustan); 'Lucaphos' (Lucava); 'Phosvit' (Nippon Soda); 'Rupini' (Ramcides); 'Swing' (Caffaro); 'Uniphos' (Florin); 'Vantaf' (Rallis)
'Equigard' (BASF); 'Nogos' (Syngenta); 'Aimdos' (Aimco); 'Didivane' (Diachem); 'Divap' (Pesticides India); 'Nuchlor' (BEC); 'Saviour' (Crop Health); 'Szklarniak' (Azot); 'Tazusa' (Vipesco); 'Vaportape' (Hercon); 'Winylofos' (Azot) Discontinued names: 'Benfos' * (Q.E.A.C.A.)
Product analysis by reaction with excess of iodine, which is estimated by titration (CIPAC Handbook, 1980, 1A, 1214) or by glc (CIPAC Proc., 1981, 3, 173). Residues determined by glc (Pestic. Anal. Man., 1979, I, 201-H, 201-I; Analyst (London), 1973, 98, 19; 1977, 102, 858; 1980, 105, 515; Man. Pestic. Residue Anal., 1987, I, 3, 6, S13, S17, S19; Anal. Methods Residues Pestic., 1988, Part I, M2, M5). Sampling of atmospheres (Anal. Methods Pestic. Plant Growth Regul., 1972, 6, 529). In drinking water, by gc with FID (AOAC Methods, 1995, 991.07). Methods for the determination of residues are available from Bayer.
Reviews FAO/WHO 68, 70 (see part 2 of the Bibliography). Food Cosmet. Toxicol., 1974, 28, 765-772; and A. S. Wright et al., Arch. Toxikol., 1979, 42, 1-18. IARC ref. 53 class 2B Oral Acute oral LD50 for rats c. 50 mg/kg. Skin and eye Acute percutaneous LD50 for rats c. 90 mg/kg. Slight skin and eye irritant (rabbits). Inhalation LC50 (4 h) for rats 340 mg/m3; (1 h) for rats 455 mg/m3. NOEL (2 y) for rats 10 mg/kg diet. ADI (JMPR) 0.004 mg/kg b.w. . Toxicity class WHO (a.i.) Ib; EPA (formulation) I EC hazard T R24/25
Birds Acute oral LD50 for bobwhite quail 24 mg/kg. Sub-acute oral LD50 (8 d) for Japanese quail 300 mg/kg. Fish LC50 (96 h) for rainbow trout 200, golden orfe 450 mg/l (both 500 EC). Daphnia LC50 (48 h) 0.19 mg/l. Algae EC50 (5 d) for Scenedesmus subspicatus 52.8 mg/l. Bees Acute oral LD50 0.29 mg/bee.
EHC 79 (WHO, 1989), 63 (WHO, 1986; a general review of organophosphorus insecticides). EHC review concludes that, with the exception of gross spillage, recommended use does not constitute a hazard for aquatic or terrestrial organisms. The high toxicity to birds and bees necessitates caution in use. Animals In mammals, following oral administration, rapidly degraded in the liver by hydrolysis and O-demethylation, with a half-life of c. 25 minutes (D. L. Bull & R. L. Ridgway, J. Agric. Food Chem., 1969, 17, 837; D. H. Hutson & E. C. Hoadley, Arch. Toxikol., 1972, 30, 9-18; A. S. Wright et al., Arch. Toxikol., 1979, 42, 1-18). Plants Rapidly decomposed in plants (D. L. Bull & R. L. Ridgway, J. Agric. Food Chem., 1969, 17, 837). Soil/Environment Non-persistent in the environment, with rapid decomposition in the atmosphere. Undergoes hydrolysis in damp media, with the formation of phosphoric acid and CO2. But G. Keller et al. (Proc. 9th IUPAC Int. Congr. Pestic. Chem., London, 1998, 2, 7C-005) say soil metabolites are dichloroethanol, dichloroacetic acid and dichloroacetaldehyde; DT50 c. 10 h. Half-lives <1 d in biologically active soils and water systems.