Suboxone

  • [Get Latest Price]
  • Narcotic & Adjuvant Drugs
  • Injections,Powder,Suspension,undefined
  • Ukraine
  • Suboxone
  • Supplier - VOLVA ENTERPRISE
  • UkraineUkraine
  • US$1 Million - US$2.5 Million
  • 11 - 50 People
  • Manufacturer,Distributor/Wholesaler
  • North America,South America,Eastern Europe,Southeast Asia,Mid East,Eastern Asia,Western Europe
  • skype
  • Mr.VOLVA
  • +380935-189614
Post Date : February 19
Product Details
Company Profile
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Item specifics

Narcotic & Adjuvant Drugs
Injections,Powder,Suspension,undefined
Ukraine

Specifications

SUBOXONE (buprenorphine and naloxone) sublingual film is an orange film, imprinted with a logo identifying the product and strength in white ink. It contains buprenorphine HCl, a mu-opioid receptor partial agonist and a kappa-opioid receptor antagonist, and naloxone HCl dihydrate, an opioid receptor antagonist, at a ratio of 4:1 (ratio of free bases). It is intended for sublingual administration and is available in four dosage strengths, 2 mg buprenorphine with 0.5 mg naloxone, 4 mg buprenorphine with 1 mg naloxone, 8 mg buprenorphine with 2 mg naloxone, and 12 mg buprenorphine with 3 mg naloxone . Each sublingual film also contains polyethylene oxide, hydroxypropyl methylcellulose, maltitol, acesulfame potassium, lime flavor, citric acid, sodium citrate, FD&C yellow #6, and white ink.

Chemically, buprenorphine HCl is (2S)-2-[17-Cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6α,14-ethano14α-morphinan-7α-yl]-3,3-dimethylbutan-2-ol hydrochloride. It has the following chemical structure:

Buprenorphine Structural Formula Illustration

Buprenorphine HCl has the molecular formula C29H41NO4 • HCl and the molecular weight is 504.10. It is a white or off-white crystalline powder, sparingly soluble in water, freely soluble in methanol, soluble in alcohol, and practically insoluble in cyclohexane.

Chemically, naloxone HCl dihydrate is 17-Allyl-4,5 α -epoxy-3, 14-dihydroxymorphinan-6-one hydrochloride dihydrate. It has the following chemical structure:

Naloxone Structural Formula Illustration

Naloxone hydrochloride dihydrate has the molecular formula C19H21NO4 • HCl • 2H 20and the molecular weight is 399.87. It is a white to slightly off-white powder and is freely soluble in water, soluble in alcohol, and practically insoluble in toluene and ether.

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