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Darunavir CAS NO.206361-99-1 factory supplies

  • [Get Latest Price]
  • China (Mainland),Shanghai
  • Aluminum foil bag
  • shanghai
  • 99%
  • Tag:Darunavir 206361-99-1 darunavir price 206361-99-1 supply Prezista TMC114
Post Date : September 10
Product Details
Company Profile

Item specifics

China (Mainland),Shanghai
Aluminum foil bag
shanghai
99%
Darunavir
white powder
by courier or by air depend on
tangfang
206361-99-1
according to MSDS
Medicine Grade
Pharmaceutical Intermediates

Specifications

Company profile:
company name:Shanghai Tangfang Biotechnology Co., Ltd.
Company set up time: December 2008.
website:http://shtangfang.en.ec21.com or http://shtangfang.lookchem.com
Skype:tangfangchem

Product introduction:
name:Darunavir
Bioavailability:37% (without ritonavir), 82% (with ritonavir)
Protein binding:95%
Metabolism:hepatic (CYP3A4)
Half-life:15 hours
Excretion:Faeces (80%), urine (14%)
CAS number:206361-99-1
ATC code:J05AE10
PubChem:CID 213039
DrugBank:DB01264
ChemSpider:184733
UNI:YO603Y8113
KEGG:D03656
ChEBI:CHEBI:367163
NIAID ChemDB:073035
Formula:C27H37N3O7S
Mol. mass:547.665 g/mol
InChI:InChI=1S/C27H37N3O7S/c1-18(2)15-30(38(33,34)21-10-8-20(28)9-11-21)16-24(31)23(14-19-6-4-3-5-7-19)29-27(32)37-25-17-36-26-22(25)12-13-35-26/h3-11,18,22-26,31H,12-17,28H2,1-2H3,(H,29,32)/t22-,23-,24+,25-,26+/m0/s1

Product information:
Darunavir is a second-generation protease inhibitor (PIs), designed specifically to overcome problems with the older agents in this class, such as indinavir. Early PIs often have severe side effects and drug toxicities, require a high therapeutic dose, are costly to manufacture, and show a disturbing susceptibility to drug resistant mutations. Such mutations can develop in as little as a year of use, and effectively render the drugs useless.

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company promises:
We could give you:
1. Best quality in your requirement
2. Competitive price in China market
3. Mature Technical support
4. Professional logistic support

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Elvitegravir CAS NO.697761-98-1

Elvitegravir CAS NO.697761-98-1

Elvitegravir CAS NO.697761-98-1

Company profile:
company name:Shanghai Tangfang Biotechnology Co., Ltd.
Company set up time: December 2008.
website:http://shtangfang.en.ec21.com or http://shtangfang.lookchem.com
Skype:tangfangchem

Product introduction:
ProName:Elvitegravir
IUPAC:6-[(3-Chloro-2-fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxoquinoline-3-carboxylic acid
CAS number:697761-98-1
ATC code:J05AX11
PubChem:CID 5277135
ChemSpider:4441060
UNII:4GDQ854U53
ChEMBL:CHEMBL204656
NIAID:ChemDB:241767
Formula:C23H23ClFNO5
Mol. mass:447.883 g/mol
Protein binding:98%
Metabolism:liver, via CYP3A
Half-life:12.9 hours
Excretion:liver 93%, renal 7%
InChI:InChI=1S/C23H23ClFNO5/c1-12(2)19(11-27)26-10-16(23(29)30)22(28)15-8-14(20(31-3)9-18(15)26)7-13-5-4-6-17(24)21(13)25/h4-6,8-10,12,19,27H,7,11H2,1-3H3,(H,29,30)/t19-/m1/s1

Product information:
Elvitegravir, used as a stand alone agent, is an investigational drug that is being studied for the treatment of HIV infection.
Elvitegravir belongs to a class (group) of HIV drugs called integrase inhibitors.2 Integrase inhibitors block an HIV enzyme called integrase. (An enzyme is a protein that starts or increases the speed of a chemical reaction.) By blocking integrase, integrase inhibitors prevent HIV from multiplying and can reduce the amount of HIV in the body.

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company promises:
We could give you:
1. Best quality in your requirement
2. Competitive price in China market
3. Mature Technical support
4. Professional logistic support

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Cobicistat 697761-98-1

Cobicistat 697761-98-1

Cobicistat 697761-98-1

Company profile:
company name:Shanghai Tangfang Biotechnology Co., Ltd.
Company set up time: December 2008.
website:http://shtangfang.en.ec21.com or http://shtangfang.lookchem.com
Skype:tangfangchem

Product introduction:
ProName:Cobicistat
IUPAC:Thiazol-5-ylmethyl N-[1-benzyl-4-[[2-[[(2-isopropylthiazol-4-yl)methyl-methyl-carbamoyl]amino]-4-morpholino-butanoyl]amino]-5-phenyl-pentyl]carbamate
CAS number:1004316-88-4
ATC code:V03AX03
PubChem:CID 25151504
ChemSpider:25084912
UNI:LW2E03M5PG Yes
ChEBI:CHEBI:72291
ChEMBL:CHEMBL2095208
Formula:C40H53N7O5S2
Mol. mass:776.023 g/mol
InChI:InChI=1S/C40H53N7O5S2/c1-29(2)38-43-34(27-53-38)25-46(3)39(49)45-36(16-17-47-18-20-51-21-19-47)37(48)42-32(22-30-10-6-4-7-11-30)14-15-33(23-31-12-8-5-9-13-31)44-40(50)52-26-35-24-41-28-54-35/h4-13,24,27-29,32-33,36H,14-23,25-26H2,1-3H3,(H,42,48)(H,44,50)(H,45,49)/t32-,33-,36+/m1/s1

Product information:
Cobicistat (COBI) is not an antiretroviral medication—it has no activity against HIV. It’s a “pharmacoenhancer” which, like Norvir (ritonavir), “boosts” drug levels of some HIV drugs, including most PIs and the integrase inhibitor elvitegravir. Cobicistat is currently only available in combination with tenofovir, emtricitabine, and elvitegravir in the form of Stribild, but we expect approval of a stand-alone version this year, as well as combinations of cobicistat with Prezista and with Reyataz. The main advantage cobicistat has over Norvir is that it will be made available for co-formulation with other drugs.

company show:

company promises:
We could give you:
1. Best quality in your requirement
2. Competitive price in China market
3. Mature Technical support
4. Professional logistic support

Detail more >>
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