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Huperzine A 99%

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  • 1 Kilogram/Kilograms
  • Other,Whole herb
  • pharmaceutical grade
  • Solvent Extraction
  • Bottle,Drum
  • Tag:Huperzine A
  • Supplier - XI'AN TIZAN TECH & INDUSTRY CO., LTD.
  • China (Mainland)China (Mainland)
  • US$1 Million - US$2.5 Million
  • 11 - 50 People
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  • North America,South America,Eastern Europe,Southeast Asia,Africa,Mid East,Eastern Asia,Western Europe
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Post Date : November 21
Product Details
Company Profile

Item specifics

Other,Whole herb
pharmaceutical grade
Solvent Extraction
Bottle,Drum
China (Mainland)
Tizan
C15H18N2O
Powder
99%
Herbal Extract
102518-79-6

Specifications

Product Name: Huperzia Serrate Extract

Plant Origin and Distribution:

Huperzia serrata (toothed clubmoss) is a plant known as a firmoss which contains the acetylcholinesterase inhibitor huperzine A. It is widely distributed over-the-counter as a nootropic and dietary supplement.

Huperzine A is extracted from Huperzia serrata. It is a reversible acetylcholinesterase inhibitor and NMDA receptor antagonist that crosses the blood-brain barrier. The structure of the complex of huperzine A with acetylcholinesterase has been determined by X-ray crystallography.

Huperzine A is a naturally occurring sesquiterpene alkaloid compound found in the firmoss Huperzia serrata and in varying quantities in other Huperzia species, including H. elmeri, H. carinat, and H. aqualupian.

Huperzine A has potent pharmacological effects, it should only be used with medical supervision. Huperzine A has been found, through multiple studies, to be effective as a medicine for helping people with neurological conditions such as Alzheimer's disease and age-related memory impairment. It has been used to treat fever and some inflammatory disorders. Huperzine A is also marketed as a dietary supplement with claims made for its ability to improve memory and mental function. Huperzine A may also have a possible role in the treatment of myasthenia gravis.

Latin Name: Huperzia serrata (Thunb. ex Murray) Trevis.

Part of Used: Whole herb

Active Ingredients: Huperzine A

CAS No.: 102518-79-6

Specification Available: Huperzine A HPLC 99%

Characteristic:

Appearance: White Powder

Odor: Characteristic

Molecular Formula: C15H18N2O

Molecular Mass: 242.32

Melting Point: 22.5°C - 226.5°C

Any Individual Impurity: 0.13%

Main Function:

  1. A cure for nonmalignant memory disorder and organic mental disorders.
  2. A cure for cerebrovascular disease and brain trauma.
  3. A cure for peripheral arterial occlusion disease and diabetic neuropathy.
  4. A cure for Achilles tendon pains and muscle trauma in sports.

Application:

  1. As pharmaceutical raw materials for clearing heat, anti-inflammation, detumescence and so on, it is mainly used in pharmaceutical field.
  2. As the raw material of product for benefiting stomach, increasing energy and boosting the immunity, widely used in health industry.

Shelf Life: 2 Years

Storage: Store in cool and dry place, keep away from light.

Packing: 25Kg/Fiber Drum, double plastic bag inside, with carton outside. 1Kg/Bag, aluminum foil bag vacuum packing.

Company Related ProductsView the Seller's Products
Mycoporphyrin 99%

Mycoporphyrin 99%

Mycoporphyrin 99%

Product Name: Hypericin

Description:

Hypericin is a naphthodianthrone, a red-colored anthraquinone-derivative, which, together with hyperforin, is one of the principal active constituents of Hypericum (Saint John's wort). Hypericin is believed to act as an antibiotic, antiviral and non-specific kinase inhibitor. Hypericin may inhibit the action of the enzyme dopamine β-hydroxylase, leading to increased dopamine levels, although thus possibly decreasing norepinephrine and epinephrine.

Hypericin was initially believed that the anti-depressant pharmacological activity of hypericin was due to inhibition of monoamine oxidase enzyme. The crude extract of Hypericum is a weak inhibitor of MAO-A and MAO-B. Isolated hypericin does not display this activity, but does have some affinity for NMDA receptors. This points in the direction that other constituents are responsible for the MAOI effect. The current belief is that the mechanism of antidepressant activity is due to the inhibition of reuptake of certain neurotransmitters. The large chromophore system in the molecule means that it can cause photosensitivity when ingested beyond threshold amounts.Photosensitivity is often seen in animals that have been allowed to graze on St. John's Wort. Because hypericin accumulates preferentially in cancerous tissues, it is also used as an indicator of cancerous cells. In addition, hypericin is under research as an agent in photodynamic therapy, whereby a biochemical is absorbed by an organism to be later activated with spectrum-specific light from specialized lamps or laser sources, for therapeutic purposes. The antibacterial and antiviral effects of hypericin are also believed to arise from its ability for photo-oxidation of cells and viral particles.

Hypericin derives from polyketides cyclisation. The biosynthesis of hypericins is in the polyketide pathway where an octaketide chain goes through processes of cylizations and decarboxylations form emodin anthrone which are believed to be the precursors of hypericin. Oxidization reactions yield protoforms which then are converted into hypericin and pseudohypericin. Theses reactions are photosensitive and take place under exposure to light and using the enzyme Hyp-1.

Botanical Source: Hypericum perforatum

Other Name: Mycoporphyrin

CAS No.: 548-04-9

Purity: ≥99%

Identification Method: Mass, NMR

Analysis Method of Purity: HPLC

Appearance: Reddish Black Powder

Odor: Characteristic

Molecular Formula: C30H16O8

Molecular Weight: 504.45

Analytical result:

Item

Specification

Results

Purity (HPLC)

≥99%

99.5%

Loss on Drying

≤2.0%

1.23%

Ash

≤0.2%

0.17%

Single impurity

≤0.5%

0.235%

Main Function:

  1. Relieves mild to moderate depression and anxiety.
  2. Promotes restful sleep.
  3. Improves capillary circulation.
  4. Increases cardiac circulation.
  5. Eases gastrointestinal distress.
  6. Relieves discomfort associated with premenstrual syndrome.
  7. Fights retroviruses.

Applications:

  1. To prevent against depression.
  2. To prevent against bacterial infections.
  3. Treatment of pre-menstrual syndrome.

Shelf Life: 2 Years

Storage: Store in cool and dry place, keep away from light.

Packing: 25Kg/Fiber Drum, double plastic bag inside, with carton outside. 1Kg/Bag, aluminum foil bag vacuum packing.

Detail more >>
Hypericin 99%

Hypericin 99%

Hypericin 99%

Product Name: Hypericin

Description:

Hypericin is a naphthodianthrone, a red-colored anthraquinone-derivative, which, together with hyperforin, is one of the principal active constituents of Hypericum (Saint John's wort). Hypericin is believed to act as an antibiotic, antiviral and non-specific kinase inhibitor. Hypericin may inhibit the action of the enzyme dopamine β-hydroxylase, leading to increased dopamine levels, although thus possibly decreasing norepinephrine and epinephrine.

Hypericin was initially believed that the anti-depressant pharmacological activity of hypericin was due to inhibition of monoamine oxidase enzyme. The crude extract of Hypericum is a weak inhibitor of MAO-A and MAO-B. Isolated hypericin does not display this activity, but does have some affinity for NMDA receptors. This points in the direction that other constituents are responsible for the MAOI effect. The current belief is that the mechanism of antidepressant activity is due to the inhibition of reuptake of certain neurotransmitters. The large chromophore system in the molecule means that it can cause photosensitivity when ingested beyond threshold amounts.Photosensitivity is often seen in animals that have been allowed to graze on St. John's Wort. Because hypericin accumulates preferentially in cancerous tissues, it is also used as an indicator of cancerous cells. In addition, hypericin is under research as an agent in photodynamic therapy, whereby a biochemical is absorbed by an organism to be later activated with spectrum-specific light from specialized lamps or laser sources, for therapeutic purposes. The antibacterial and antiviral effects of hypericin are also believed to arise from its ability for photo-oxidation of cells and viral particles.

Hypericin derives from polyketides cyclisation. The biosynthesis of hypericins is in the polyketide pathway where an octaketide chain goes through processes of cylizations and decarboxylations form emodin anthrone which are believed to be the precursors of hypericin. Oxidization reactions yield protoforms which then are converted into hypericin and pseudohypericin. Theses reactions are photosensitive and take place under exposure to light and using the enzyme Hyp-1.

Botanical Source: Hypericum perforatum

Other Name: Mycoporphyrin

CAS No.: 548-04-9

Purity: ≥99%

Identification Method: Mass, NMR

Analysis Method of Purity: HPLC

Appearance: Reddish Black Powder

Odor: Characteristic

Molecular Formula: C30H16O8

Molecular Weight: 504.45

Analytical result:

Item

Specification

Results

Purity (HPLC)

≥99%

99.5%

Loss on Drying

≤2.0%

1.23%

Ash

≤0.2%

0.17%

Single impurity

≤0.5%

0.235%

Main Function:

  1. Relieves mild to moderate depression and anxiety.
  2. Promotes restful sleep.
  3. Improves capillary circulation.
  4. Increases cardiac circulation.
  5. Eases gastrointestinal distress.
  6. Relieves discomfort associated with premenstrual syndrome.
  7. Fights retroviruses.

Applications:

  1. To prevent against depression.
  2. To prevent against bacterial infections.
  3. Treatment of pre-menstrual syndrome.

Shelf Life: 2 Years

Storage: Store in cool and dry place, keep away from light.

Packing: 25Kg/Fiber Drum, double plastic bag inside, with carton outside. 1Kg/Bag, aluminum foil bag vacuum packing.

Detail more >>
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