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Hesperetin 90% 95% 98% HPLC - Citrus Aurantium Extract Wholesale

  • USD 100 - 100 / Kilogram  [Get Latest Price]
  • 1 Kilogram/Kilograms
  • Bark
  • Cosmetics & Food & Medical Grade
  • Solvent Extraction
  • 520-33-2
  • Tag:Hesperetin
  • China (Mainland)China (Mainland)
  • US$1 Million - US$2.5 Million
  • 11 - 50 People
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Post Date : August 14
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Item specifics

Cosmetics & Food & Medical Grade
Solvent Extraction
China (Mainland),Shaanxi
90%, 95%, 98% HPLC
Herbal Extract
226228 °C



What is Hesperetin?

Hesperetin is the 4'-methoxy derivative of eriodictyol, a flavanone. Hesperetin's 7-O-glycoside, hesperidin, is a naturally occurring flavanon-glycoside, the main flavonoid in lemons and sweet oranges. Hesperetin and naringenin are not found to a significant extent in Citrus spp.

Hesperetin is mainly coming from the enzymolysis of hesperidin with the functions of invigorating the stomach, eliminating phlegm, preventing cough, expelling rheumatism, treating diuresis, anti-virus, anti-microbial, treating non-return and relieving stomachache, widely used in the food, pharmaceutical and healthcare product industry etc.

Hesperitin Benefit

A high-vegetable diet with various fruits and vegetables daily including on average one glass of orange juice, one-half orange and one-half mandarin provides 130 mg of hesperetin and 30 mg of naringenin.

Hesperitin has antioxidant and anti-inflammatory properties. Hesperidin can also act as a vasodilator, which may be useful in Hypertension.

Health-promoting Effects of the Citrus Flavanone Hesperidin. Preclinical studies and clinical trials demonstrated therapeutical effects of hesperidin and its aglycone hesperetin in various diseases, such as neurological disorders, psychiatric disorders and cardiovascular diseases and others, due to its anti-inflammatory, antioxidant, lipid-lowering and insulin-sensitizing properties.

Hesperetin and its anti-neoplastic effects in systemic malignancies. Comment on Hesperetin impairs glucose uptake and inhibits proliferation of breast cancer cells.

Identifiers & Properties of Hesperetin




90%, 95%, 98% HPLC


White Powder



CAS Number








ECHA InfoCard


EC Number




PubChem CID




Chemical formula


Molar mass

302.28 g mol−1

Melting point

226–228 °C (439–442 °F; 499–501 K)


Easily soluble in ethanol, soluble in diluted alkali solution, partly soluble in diethyl ether, slightly soluble in water, chloroform and benzene

Tizan Hesperetin Characteristics

Tizan supply hesperetin which is stable and not easy to hydrolyze or degrade with the properties of high bioavailability, stable effect, precise bioactivity, stability and lower toxicity.

Main Function of Hesperetin:

1. Hesperetin has remarkable function of anti-inflammation and antioxidant.

2. Hesperetin has significant regulation and inhibition function of cardiovascular protection and reducing blood lipid.

3. Hesperetin effect avoiding canceration and inhibit cancer cell proliferation, has anti-tumor and anti-cancer effection.

4. Hesperetin reduces toxicity damage of nervous excitability and protect the nervous system.

5. Hesperetin get greater role in promoting the p-glycoprotein mediated drug flowing from tumor cells.

Shelf Life: 2 Years

Storage: Store in cool and dry place, keep away from light.

Packing: 25Kg/Fiber Drum, double plastic bag inside, with carton outside. 1Kg/Bag, aluminum foil bag vacuum packing.

Company Related ProductsView the Seller's Products
Huperzine A 99%

Huperzine A 99%

Huperzine A 99%

Product Name: Huperzia Serrate Extract

Plant Origin and Distribution:

Huperzia serrata (toothed clubmoss) is a plant known as a firmoss which contains the acetylcholinesterase inhibitor huperzine A. It is widely distributed over-the-counter as a nootropic and dietary supplement.

Huperzine A is extracted from Huperzia serrata. It is a reversible acetylcholinesterase inhibitor and NMDA receptor antagonist that crosses the blood-brain barrier. The structure of the complex of huperzine A with acetylcholinesterase has been determined by X-ray crystallography.

Huperzine A is a naturally occurring sesquiterpene alkaloid compound found in the firmoss Huperzia serrata and in varying quantities in other Huperzia species, including H. elmeri, H. carinat, and H. aqualupian.

Huperzine A has potent pharmacological effects, it should only be used with medical supervision. Huperzine A has been found, through multiple studies, to be effective as a medicine for helping people with neurological conditions such as Alzheimer's disease and age-related memory impairment. It has been used to treat fever and some inflammatory disorders. Huperzine A is also marketed as a dietary supplement with claims made for its ability to improve memory and mental function. Huperzine A may also have a possible role in the treatment of myasthenia gravis.

Latin Name: Huperzia serrata (Thunb. ex Murray) Trevis.

Part of Used: Whole herb

Active Ingredients: Huperzine A

CAS No.: 102518-79-6

Specification Available: Huperzine A HPLC 99%


Appearance: White Powder

Odor: Characteristic

Molecular Formula: C15H18N2O

Molecular Mass: 242.32

Melting Point: 22.5°C - 226.5°C

Any Individual Impurity: 0.13%

Main Function:

  1. A cure for nonmalignant memory disorder and organic mental disorders.
  2. A cure for cerebrovascular disease and brain trauma.
  3. A cure for peripheral arterial occlusion disease and diabetic neuropathy.
  4. A cure for Achilles tendon pains and muscle trauma in sports.


  1. As pharmaceutical raw materials for clearing heat, anti-inflammation, detumescence and so on, it is mainly used in pharmaceutical field.
  2. As the raw material of product for benefiting stomach, increasing energy and boosting the immunity, widely used in health industry.

Shelf Life: 2 Years

Storage: Store in cool and dry place, keep away from light.

Packing: 25Kg/Fiber Drum, double plastic bag inside, with carton outside. 1Kg/Bag, aluminum foil bag vacuum packing.

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Mycoporphyrin 99%

Mycoporphyrin 99%

Mycoporphyrin 99%

Product Name: Hypericin


Hypericin is a naphthodianthrone, a red-colored anthraquinone-derivative, which, together with hyperforin, is one of the principal active constituents of Hypericum (Saint John's wort). Hypericin is believed to act as an antibiotic, antiviral and non-specific kinase inhibitor. Hypericin may inhibit the action of the enzyme dopamine β-hydroxylase, leading to increased dopamine levels, although thus possibly decreasing norepinephrine and epinephrine.

Hypericin was initially believed that the anti-depressant pharmacological activity of hypericin was due to inhibition of monoamine oxidase enzyme. The crude extract of Hypericum is a weak inhibitor of MAO-A and MAO-B. Isolated hypericin does not display this activity, but does have some affinity for NMDA receptors. This points in the direction that other constituents are responsible for the MAOI effect. The current belief is that the mechanism of antidepressant activity is due to the inhibition of reuptake of certain neurotransmitters. The large chromophore system in the molecule means that it can cause photosensitivity when ingested beyond threshold amounts.Photosensitivity is often seen in animals that have been allowed to graze on St. John's Wort. Because hypericin accumulates preferentially in cancerous tissues, it is also used as an indicator of cancerous cells. In addition, hypericin is under research as an agent in photodynamic therapy, whereby a biochemical is absorbed by an organism to be later activated with spectrum-specific light from specialized lamps or laser sources, for therapeutic purposes. The antibacterial and antiviral effects of hypericin are also believed to arise from its ability for photo-oxidation of cells and viral particles.

Hypericin derives from polyketides cyclisation. The biosynthesis of hypericins is in the polyketide pathway where an octaketide chain goes through processes of cylizations and decarboxylations form emodin anthrone which are believed to be the precursors of hypericin. Oxidization reactions yield protoforms which then are converted into hypericin and pseudohypericin. Theses reactions are photosensitive and take place under exposure to light and using the enzyme Hyp-1.

Botanical Source: Hypericum perforatum

Other Name: Mycoporphyrin

CAS No.: 548-04-9

Purity: ≥99%

Identification Method: Mass, NMR

Analysis Method of Purity: HPLC

Appearance: Reddish Black Powder

Odor: Characteristic

Molecular Formula: C30H16O8

Molecular Weight: 504.45

Analytical result:




Purity (HPLC)



Loss on Drying






Single impurity



Main Function:

  1. Relieves mild to moderate depression and anxiety.
  2. Promotes restful sleep.
  3. Improves capillary circulation.
  4. Increases cardiac circulation.
  5. Eases gastrointestinal distress.
  6. Relieves discomfort associated with premenstrual syndrome.
  7. Fights retroviruses.


  1. To prevent against depression.
  2. To prevent against bacterial infections.
  3. Treatment of pre-menstrual syndrome.

Shelf Life: 2 Years

Storage: Store in cool and dry place, keep away from light.

Packing: 25Kg/Fiber Drum, double plastic bag inside, with carton outside. 1Kg/Bag, aluminum foil bag vacuum packing.

Detail more >>
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